Hagop Kantarjian Selected Research

Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

1/2022	The Evolution of Research and Therapy With Hypomethylating Agents in Acute Myeloid Leukemia and Myelodysplastic Syndrome: New Directions for Old Drugs.
1/2022	Prediction of survival with intensive chemotherapy in acute myeloid leukemia.
1/2022	Prediction of early (4-week) mortality in acute myeloid leukemia with intensive chemotherapy.
1/2022	Hypomethylating agent and venetoclax with FLT3 inhibitor "triplet" therapy in older/unfit patients with FLT3 mutated AML.
11/2021	Development of TP53 mutations over the course of therapy for acute myeloid leukemia.
10/2021	When Less Is More: Reevaluating the Role of Intensive Chemotherapy for Older Adults With Acute Myeloid Leukemia in the Modern Era.
1/2021	Core binding factor acute myelogenous leukemia-2021 treatment algorithm.
1/2021	The Clinical impact of PTPN11 mutations in adults with acute myeloid leukemia.
1/2021	Phase 1 dose escalation trial of volasertib in combination with decitabine in patients with acute myeloid leukemia.
1/2021	IDH1/IDH2 Inhibition in Acute Myeloid Leukemia.

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Hagop Kantarjian Research Topics

Disease

211	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 09/2022 - 01/2000
186	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 01/2002
125	Neoplasms (Cancer) 10/2022 - 01/2002
120	Leukemia 09/2022 - 03/2002
113	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 05/2022 - 01/2002
112	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 03/2002
72	Philadelphia Chromosome 01/2022 - 02/2002
40	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 03/2002
37	Primary Myelofibrosis (Myelosclerosis) 12/2021 - 09/2002
34	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 01/2002
27	Acute Promyelocytic Leukemia 01/2020 - 05/2003
24	Thrombocytopenia (Thrombopenia) 01/2022 - 04/2004
23	Blast Crisis (Blast Phase) 01/2021 - 10/2002
23	Residual Neoplasm 01/2021 - 11/2006
20	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2021 - 06/2002
18	Anemia 01/2022 - 03/2002
18	Myeloid Leukemia (Leukemia, Myelocytic) 01/2021 - 04/2006
17	Disease Progression 12/2021 - 05/2002
15	Infections 01/2022 - 03/2003
15	Lymphoma (Lymphomas) 01/2022 - 06/2005
14	Chromosome Aberrations (Chromosome Abnormalities) 01/2022 - 05/2002
11	Splenomegaly 01/2018 - 03/2002
11	Myeloproliferative Disorders (Myeloproliferative Disorder) 06/2008 - 09/2002
10	Pneumonia (Pneumonitis) 01/2022 - 01/2003
10	Multiple Myeloma 10/2017 - 03/2003
10	Polycythemia Vera 04/2017 - 06/2003
9	Exanthema (Rash) 01/2021 - 06/2009
9	Pathologic Complete Response 07/2020 - 01/2003
9	Neutropenia 02/2019 - 09/2003
9	Nausea 09/2018 - 10/2002
9	Hypereosinophilic Syndrome (Loeffler Endocarditis) 06/2013 - 09/2002
8	Hemorrhage 11/2019 - 06/2009
8	Fever (Fevers) 10/2018 - 01/2003
7	Diarrhea 01/2017 - 12/2003
7	Systemic Mastocytosis 09/2013 - 05/2004
7	Essential Thrombocythemia 08/2013 - 01/2003
6	Hypertension (High Blood Pressure) 12/2020 - 01/2011
6	Burkitt Lymphoma (Burkitt's Lymphoma) 12/2020 - 03/2002
6	Sepsis (Septicemia) 07/2020 - 08/2004
6	Cytopenia 01/2020 - 06/2007

Drug/Important Bio-Agent (IBA)

148	Imatinib Mesylate (Gleevec)FDA Link 01/2020 - 01/2000
85	Tyrosine Kinase InhibitorsIBA 01/2022 - 11/2006
56	Cytarabine (Cytosar-U)FDA LinkGeneric 05/2022 - 03/2002
37	Dasatinib (BMS 354825)FDA Link 11/2020 - 06/2006
36	Decitabine FDA Link 12/2021 - 03/2003
32	Proteins (Proteins, Gene)FDA Link 01/2019 - 03/2002
30	Pharmaceutical PreparationsIBA 10/2021 - 04/2004
28	Phosphotransferases (Kinase)IBA 06/2018 - 12/2003
23	Rituximab (Mabthera)FDA Link 12/2021 - 11/2003
23	fludarabineIBA 12/2021 - 03/2003
23	nilotinib FDA Link 03/2016 - 07/2005
22	bcr-abl Fusion ProteinsIBA 01/2022 - 01/2000
21	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2021 - 03/2002
21	Monoclonal AntibodiesIBA 01/2021 - 09/2004
20	Azacitidine (5 Azacytidine)FDA Link 01/2019 - 01/2005
19	Arsenic Trioxide (Trisenox)FDA Link 01/2021 - 05/2003
19	Clofarabine (Clolar)FDA Link 01/2021 - 10/2003
18	ponatinibIBA 09/2022 - 11/2012
18	Inotuzumab OzogamicinIBA 01/2022 - 06/2013
18	Vincristine (Oncovin)FDA LinkGeneric 10/2021 - 03/2002
16	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2019 - 05/2003
15	InterferonsIBA 01/2021 - 03/2003
15	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2018 - 01/2003
14	Gemtuzumab (Mylotarg)FDA Link 01/2020 - 01/2002
13	ruxolitinibIBA 01/2021 - 04/2010
13	Interferon-alpha (Interferon Alfa)IBA 06/2012 - 01/2000
12	venetoclaxIBA 05/2022 - 03/2014
12	blinatumomabIBA 01/2022 - 01/2017
12	ibrutinibIBA 12/2021 - 06/2014
12	Dexamethasone (Maxidex)FDA LinkGeneric 10/2021 - 03/2002
12	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2021 - 03/2002
11	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2002
11	Core Binding Factors (Core-Binding Factor)IBA 01/2021 - 12/2008
11	DNA (Deoxyribonucleic Acid)IBA 10/2020 - 12/2003
11	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2015 - 03/2003
10	Lenalidomide (CC 5013)FDA Link 10/2022 - 05/2007
10	Hemoglobins (Hemoglobin)IBA 07/2018 - 06/2004
9	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 06/2014
9	CytokinesIBA 12/2021 - 09/2002
9	Sorafenib (BAY 43-9006)FDA Link 11/2020 - 12/2008
9	fms-Like Tyrosine Kinase 3IBA 01/2020 - 05/2004
8	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2022 - 03/2002
8	Alemtuzumab (Campath)FDA Link 06/2013 - 11/2005
7	Biological ProductsIBA 01/2021 - 05/2004
7	HomoharringtonineIBA 01/2019 - 01/2007
7	Prednisone (Sone)FDA LinkGeneric 12/2018 - 09/2010
7	Methotrexate (Mexate)FDA LinkGeneric 01/2016 - 03/2002
7	Alkylating AgentsIBA 06/2012 - 05/2004
7	tipifarnib (R115777)IBA 03/2011 - 10/2002
6	CreatinineIBA 01/2022 - 10/2008

Therapy/Procedure

287	Therapeutics 10/2022 - 03/2002
98	Drug Therapy (Chemotherapy) 07/2022 - 03/2002
23	Stem Cell Transplantation 01/2022 - 07/2003
20	Salvage Therapy 01/2022 - 04/2003
14	Hematopoietic Stem Cell Transplantation 01/2020 - 02/2007
14	Induction Chemotherapy 01/2017 - 01/2003
8	Transplantation 01/2022 - 09/2003
7	Drug Tapering 11/2020 - 12/2003
6	Radiotherapy 10/2022 - 09/2004
6	Cell Transplantation 01/2022 - 01/2007